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lliiiKirm and Blettt. Wlicn 'é board of eminent physicians and chemists anoounocd the discovery tliat by oomblniojC some well knowu valuable remedies the mogt wónderfiU medicine, was produced, wliioli would curo such a wido range of discjix's that mogt all other remÊ. could le dispenced wilh; inany were skepttcsl, im.i. -m( of its merits by actual trial hiis dispelled ill dontn, a to-dav tfae dJacoveren of that great mediciiu, flop Bitten, are bonorad and blesscd by all as benefactoi-s. - DciiuxTai. Tuke Ayers Pilis for all the purposes of a purgativa, for Constiparon, indigestión, Hcadachc and Liver Complaint. üy universal accord, they are the best of all purgativos for family use, East 8A0INw, Jan. 12, 1881. Mk. W. U. Moobb: Dkak Sir:- About the first of December I was taken with a very severe attack of rheumaUsm In both of my knees. I was recommended to use Dinc's Cajumkihatkd Ahkica. I can cheerfully rcromniend it to every one troubled wltli rlRiiniatism. m. E. HHADV. 1IW.5.S Gooi) Ad k k. Weadvise every farally to keep Downs' Kuxih ulwayn on hand. It is the best reinedy for 0OUgB8 and colüs ever offered to the public. For clcansing the system of all inoibM matter and waiding off diseases, no medicine poBsesses sucn eflicacy as Baxtkk's IIandkake Ditters. Aí a Linimentfor horsts Hkskv& John8O"8 AHNIOA AND Olí. I.IN1MKNT is 1111cciiakd. It cures Spnvins, Bniises, and Lameness, at once. INGHAM UNIVERSITyToR LADIES I.m K) . Uenesre to., N. . The turty. Btventh yeiir opun Xcpt. S:h, IHÜl. Ful] College Curricnlum. Olanslcal nd Literary Couraca. School of Miisic, adoptlDK Germán and Oonurrvatory lm. provementa. Collefrt) oí Kiuu Arta, iurQiu th b t methwU of the Kiiriipcuii Schools of Art. Best odnraüontt] advamages. Loweat teruiK. For ri loquea addresn II. J. HCHJtlT., Treaturor. a IN YOÜR MAGAZINES ! PAMPHLETS, ETC, AUD HAVE THEH BflüND ! NOW IS THE TIME