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Dr. J. Walker's California Vin w;ar Bitters aro a purely Voge pieparation, made chiefly frora the es. ti% e herbs found on the fowcr ranges tht .Sierra Nevada mountains of Caliioi nuv the medicinal proporties of' are estracted tborefrom without thense ■of Alcoboï. The question ia almost daily asked, ' Wbat is tbo cause of tho unpáralleled success of Vixegae Bit'Cers?" Our answcr is, tbat they remov? íhe causo of disease, and the patiei covers b.is bealtb. They are the g blood purifier and a life-gi ving priiü a perfect Kenovator and Invigi of the Nevel before ii h3tory 3f the world has a medicine bees compounded jpoBKessing the rema: qualities of Tinegar Bitters iu healingti.' siok oí' every disease man is heir to, The; are a gentle Purgativo as well as a Tonís, -eLbving Congestión or Iníiamuiation oi the Liver and Vkceral Organs, in Bi S'.ueases. The propertíes -J De, Walxees Yinügar Bitters are Apenen t, Diap'aoreüc Carminative, ííutntions, Laxative, Diuretit tjedative, Counter-Irritant, Sudorino,Alfc tjve. and Antí-Büiona Gratef'u' Tuonsamls prodaimVnr egar Brrria íiie most wonderfal ínvigoraut that ver sustained the sinkiu system. ' No Person can tnke these Bitters according to directions, and remainlong univell, provided their bonus are not destroyed by mineral poison or othei meaus, and vita,! orgaus wasted bevond repair. Bilions, Renrittent and íntermittent Fevers, which are so prevalent in the valleys of our great rivera throughout the United States, especially those of the Mississippi, Ohio, Missouri, Illinois, Tennessee, Cumberland, irkajjsas, Red, Colorado, Brazos, J.'io Orante, Pearl, Alabama, Mobüo, Savannab,Koanoke, James, n'.id many otbers, with their vast tributarios, th'ougliout our entire country during the Summer and Autuiun, and reinarkably so during se;isons of unusual heat and dryness, ara invariably accorapanied by cxtensivencrangemcnts of the storaach and liver, and otber abdominal viscera. Iu their troatmcnt, a purgativo, exertiug a powerful inliuence upon these various or saus, is essential'y necessary. Thcre is no eatbartic for the purpose equal to Dn. .1. Walker's Vixküak Bittebs, as they wil] speedily remove the darkcolored viscid matter with which the bowels are loaded, at the same time stiiiuüatjng the secretions of tho liver. and generally restoring tho heaithy fuuctions of the digestivo organs. Foriify the boly against disease by purifying all its tluidswith Vinegab Bitteiis. No epidemie eau tako bold of a systeiu thus fore-armed. Dj spepsia or Indigestión, Headache, Pain iu tho Shoulders, Congh3, Tightness of tho Chest, Dizziness, Soiir Eructations of the Stomach, Had Taste in tho Mouth, Bilious Attacks, Palpitatation of the [Ieart, Inrlainmatiou of the Lungs, Pain in the región of the Kidneys, and a hundred other painful symptonis, are the offsprings of Dyspepsia. One bottlewill prove a botter guaramos of its merite tb.au a lengthy advertisement. Scrofnla, or King's Evil, White Swelliiigs, Ulcera, Erysipclas, Swelled Net-k. Goitre, Scrofulous iñflainmatious, Indolent Inflammations, Mercurial Affcctions, OW Sores, Eraptions of the Skin, Soro Eves, eic In these, as in all other constitutional D eases, Walkkr's Vinkgar Bittüks havo sliowa thoir great curativo powera in "' most obstinate and intractahle cases. For In(inniniator.y and Ciñóme Ithenmatisni, Gout, Bilious, Keniitteut and Intermittent Fevers, Diseasesol the Blood, Liver, Kidneys and Bhi these Bitters have no equal. Such Dis are eauaod by Vitiated Blood. Mechanical Diseases.- Persons wgaged in Paints and Minerals, suco M 'lumbers, Type-setters, Gold-beaters, Minera, as they ad vaneo in lile, are subject to paralysis of the Bowels. To g against this. take a dose of Walker's KOAR BlTTKRS occasionally. For Skin Diseases, Eruptiogs, T ter, Salt-Klienin, Blotches, Spots, Rmpl PtaBtnles, Boils, Carbunclos, Ring-worm Scald-head, Sore Kves, Erysipelas, It Scuffs, Discolorations of tbc Skin, Hinn"r' and Disoasea of the Skin of whatever naine or nature, are litêrally dng np and cam out of the system in a short time by the usi of these Bitters. Pin, Tape, and other Worm lurking in the system of so many thoneaaW are efl'eotually destreyed and removed. Bvstem rif medicine, no vermifuges, no a' thelminitics will free the system froin worms liko these Bitters. For Feniale Coinplaints, inyoung or old, married or single, at the dawu "', iV0' manhood. or the turn of lite, these ïo:' Bitters display so decided an influence taai improvement is soou perceptible. Cleanse the Vitiated Blood whenever vonfind its impnrities hurstine tbroiipj the kin in Pimples, Emptions, or ■ -"j cleanse it wheu you find it obstructeu a sluggish in theveius; cleanse it whenit foul ; your feelings will teil vou when. ev the blood pure, and the heaïth of the systeul will follow. IS. H. MCDONALD & CO.. Drugïists and Gen. Acts., San Francisoo. CaBB"1 and cor. of WiiatóDgton and Ghartton st., ' Sol) ly ui) UriiBS" ;l1(' -'' "xU ' ' Ivo ovi'ivrv.ii STORIBS; ._ TERMS OF SUBSCBIPTION, POSTAGB '„:".,'-„ OSK IK Alt, -.. G MdVrils ' GREATPREMII'JI OPI ■ ■' ■ l. The cholee of two beiauiful SU'el K ■ i ' "OOCKMNCtS" and " T1ÍE l"1, ' SI Vx OU TIIf C -IIOlfK PLDWËB SE"" or buth Knpr.iviiifis, to ejicli yoaily iubscriber. , (i,e CO nCIITC For tllisamr.unt viposipaiti. Aiicnïs :! ii-i eve-yvlicre ,„}iix BBKIjY.raaChesln aw.p. ':;'- WHEN WU1TIHG TO AVEBTIS V T 1I nsc say yon saw tlti iidreo'-' Ui tjliii paper