Among all the known remedies for diseiise none perhaps lias such universal use as quinine. In its place it may be regarded as a speciflc, and a Samson in accomplishing its work. The discovery of quinine is of comparatively recent date, having been made by a Erench chemist, Pelletier, about sixty years ago, and for which discovery the French Academy awarded him a prize of ten thousand francs. lts value in all forms or fever, especially those of remittent and intermittent forms, can not be overestimated. As a tonic and a piophylactic in all malarial districts, no known remedy can for a moment be compared to it, and it would be difficult to find a substitute in case the supply should become exhausted. ïhe liigh price of the genuine Bollivian cinchona calisaya, owing to its universa' use and the limited región from which it is obtained, offers great temptation to palm off upon the market other tlian the genuine. The barks thus obtained furnish quinidine, instead of quinine and the article in the market is thui largely diluted and impoverished, anc the human family suffers in consequence. Considerable attention has been attracted to this imposition, and the careful physician depends much upon the name of the manufacturing chemist. "While the quinine, as we reniarked, was discovered only sixty years yet the chinchona bark has been a well-known remedy for over two centimes. In fact tliere is a romance about its discovery and its name. In 1838 the Countess of Cinchón, the wife of the Governor of Peru, was seized witli a violent fever, and was cured by au infusión of wliat was known before as Peruvian bark, or Jesuits' bark. From this fact the name of the Countess was associated with the bark. and from Cinchón it has become Cinchona. It is found growing on the high lands of Peru, New Grenada, Ecuador, and Bolivia. It grows in isolated clusters from fi.OOO to 10,000 feet above the sea level, and it is a work of great hardship to gather it for the market. The foresta are dense, and every foot of the way lias to be hewn through to reach the trees in their high position. The trees grow about eighty feet in lieighth, and every part of the tree is robbed of its bark and destroyed when found. The attempt to grow these trees in other latitudes lias frequently been made, and with some degree of success. The Germán Government, in 1854, sent au expeditión to Peru, and a large number f' planta were obtained and planted in Java, and the promise there is good. In 1860, through the intluence of the East India Company, Sir llobert Christison, and Dr. Boyle, a se ond planting of trees was made in Soathern India, Ceylon, and upon the slopes of the Ilimalayas, as well as in British Burmah and the island of Mauritius. The reports from these 1 ■ calities as to the thrift of the plants are most gratifying, and removes the well-grounded fears which vvere before entertained, that in a few years the cinchona forests would be anniliitated.