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DETROIT, HILLSDALE AND 8OUTHWESTEKN KAILROAD. To take effect May 25, 1879. OOINÍi WKST. OOINO EA8T. TATIO KB. Mail. Kip. ; STATIONS. Éxp. Mail a. m. r.v. YpBilanti.... 8:35 7:10 A. m. p. M. Toledo June. 8:45 7:30 Banken 6:00 2:25 Saline 9:25 7:50 I Hillsdale ... 5:30 2:S5 Bridgewater.. 9:47 8:12 Manchester.. 8:S0 4:11 Manchester. 10:22 8:37 Bridgewater 9:00 4:30 r. M. Saline 9:50 4:47 Hilladale 1:00 10:25 , Toledo Juno. 10:10 4:57 Bankers 1:10 10:35 ! Tp8ilanti.. . . 10:35 5:15 Traína run by Chicago time. W. F. PAKKER, Sup't, Ypsilanti. TlJANHOOI): How Lost, How Restored. #Jut publishod, a now edition of Db. Culvkuwell'b Celebkated Essay on the radical cure (without medicine) oí Bpebmatorrhcea or Seminal Weakneas, Iuvoluntary Seminal Loases, Impotkncy, Mental and Physical Incapacity, Impedimenta to Mar riage, etc.; alao, Comsumptiok,Epilepst and Fits, induced by self-indulgenee or sexual extrayaganca, &c. The celebrated author, ín this admirable Estay, olearly demonstrates, from a thirty years successíul practice, that the alarming consequences of selfabutte may be radicaily oured without the danger oub use of internal medicine or the application of the knife; pointing out a mode of cure at once sim. pie, certain, and effertual, by means of which every suíterer, no matter what his condition may be, may cure himself cheaply, privately, and radicaily. - This Lecture should be in the hands of every youth and every man in the land. Sent tree, under sea!, in a plain envelopí, to Huy addreiw. Address the Publishers. The Culverwell Medical Co., 41 Asn St., New Yobk; Post Office Box, 4586. ORAï'S SPECIFIC MEDICINE. TRADEMARK.T1;e Oreat En. TRADËMK. B'Jffv lor Seminal JB V BeforeTakingLossof MnoryAfter Takiug. Univeral Laasitude, Pain in the Back, Dimness of Vision, Premature Uld Age, and many other diseases that laad to Insanity, Consamption and a Prematnre Orave. Full particular in our pamphlets, which we deaire to send free by mail to every one. The Speoiflc Medicine is sold by all DruggiaU at $1 per package, or six paokagea for $5, or will be sent by mail on receipt of the money by addressing THE (1BAY MEDICINÉ CO., No. 10 Mechanica' Bloek, Detroit Mioh. 49-Sold In Ann Arbor by all Druggiata, and b druggUti ererywhere