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A General Tie-up. of all means oi public conveyance in ,-i large clty, even for a few hours, during strike of the employés, means a general paralyztng oí tra.de and industry for the Time betog, and is attended witli au enonnous aenre■aio Uiss to the commnnity. lli" iiiiic!i more serioua to ihc individual is the general tie-njp at hls Bystem, kmnni as constlpation, and dne to the strike of the most important organs (or more prudent treatnunir anil bet ter care. Tí too long neglected, a torpld or Blugglsh lipr-Yilí produce serlous forms Of kidney and livor discases, nialarial trouble and chronlc dyspepsla. Dr. Piercé's Pleasant Purgative Pellets are a preventlve and cure of these disorders. T)y ore prompt. Bure and effectlve, pleasant to taike, and posltively barmlesB.