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When the appetite fails there is no use in trymg to tempt the palate with delicate food. No matter how good and well-cooked and appetizing" the food may be, it cannot give any nourishment unless the stomach is able to digest it. Nature indicates the state of the constitution by the loss of appetite. Tnis is an unfailing indicator. It shows that something is fundamentally wrone with the nutritive functions. The only true natural relief must be as searching and fundamental as the trouble it aims to overeóme. It is the thorough deepsearchmg eharacter of Dr. Pierce's Golden Medical Discovery, which causes the marvelous efficacy in all bilious and digeitive difficulties. It creates that healthful vitality pt the entire digestive and nutritive organism which produces both the natural desire for food and the organic capacity to assimilate and transform it into nourishing, revivïfying blood and healthy tissue. It gives appetite, digestión and sound sleep, and builds up solid muscular strength and vital nerve - energy. H. H. Thompson, Esq., of P. O. Box 4, Kipple Blair Co., Penn'a, writes: " I had been troubled' with extreme vomiting in summer season always after eating; had to be very careful at times to get anything to stay on tny stomach at all ■ had been taknigr other medicines, but without eiïect I heard a fnend speak of Dr. Pierce's Golden Medical Discover}', and thought I would give it a tnal. I used about five bottfes of it and think it Is the only medicine that did me any good as I have a splendid appetite now, and am not úsing any medicine at all and don't think I need any A man who is suffering from the evil effects of constipation doesn't feel like work, and can't even enjoy his leisure nours. D?. nerce's Pleasant Pellets are a sure, swift, safe, and permanent cure for constipation. They are tiny, sugar-coated granules. One little "Pellet" is a gentle laxative, and two a mild cathartic They never gripe. Dishonest druggists try to get you to 'cake a substitute for the ake of the addedjirofit.