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A DOCTOR'S EVIDENCE. The Rationale of the Cure of Chromc . Catarrh. How Permanent Cures are Made. The order in which the symptoms of chronic catarrh occur are nearly always as follows: A cold, which hangs on longer than usual; a sensitiveness of the air passages by which one catches cold easily; a continual settled cold in head, throat or chest; discharges growing thicker and more offensive: loss of flesh, despondency, loss of appetite, headache or cough, and general lassitude. Now this is about the order in which symptoms of chronic catarrh make their appearance, and if the sufferer is fortúnate enough to .find a cure the symptoms will begin to disappear in exactly the reverse order. There may be at first no perceptible improvement in the earliest symptoms while the latter symptoms show prompt improvement. This is exactly what Pe-ru-na will do in the cure of chronic catarrh: It first invigorates the system, increases the appetite, then the patiënt begins to gain flesh, hope takes the place of despondency, and all the r.ist'hievous symptoms which the chr )nic catarrh has produced will disappear one by one in the reverse order of their appearance. The last symptoms to yield are often the ones which the patients expset to disappear first, but all should remember that the first symptoms to appear will be the last to disappear, while the last ones to appear are usually the first ones to disappear. Cures made in this way are permanent cures. A patiënt cured by Pe-ru-na is no more liable to catarrh than as if he had uever had it. A complete treatise on chronic catarrh in all its stages and complications will be sent free, on application by The Pe-ru-na Drug Manufacturing Company of Columbus, Ohio. A new remedy has created a sensation among physicians by its wonderful effects in speedily curing every form of Piles. It is called the Pyramid Pile Cure. It is cheap and simple to use, but nothing removes the disease so quickly, safely and surely. Any druggist will get it for you.