Vv'ashington, June 22.- Únele Sam is likely to have a great deal of trouble with the Japanese over Hawaii. The Japanese minister flled at the state department a protest against the proposed annexation oí Hawaii to the United States. The protest is based upon the contention that Japan has a treaty with Hawaii which permits the migration of Japanese subjeets to the islands under certain conditions. Pursuant to the terms of that treaty large numbers of Japanese have made Hawaii their home. If now the United States annex the islands these subjeets of the mikado will lose the rights which they have obtalned, as the system of the United States is vastly different from that of Hawaii. The Japanese claim that they are so largely interested in Hawaii that they should have been consulted as to annexation. They contend that their interests are so great as to entitle them to consideration. Of course it is well understood that Japan is aggrieved because she had designs of her own upon Hawaii, and because the United States has stepped in and beaten her at her own game. The president and Secretary Day are not at all worried about Japan's protest. That there will be more or less friction with the mikado's government before all the affairs of the three natlons Incident to annexation are flnally arranged is expected. But that they will be amicably adjusted in the end no one doubts. At the same time most of the administration do not conceal that they have a little anxiety as to what may have happened in Hawaii since the last steamer left Honolulú. There have been rumors of the appearance in that harbor of one or two Japanese cruisers, and also muttering-s of an uprising among the native Kanakas. The next steamer from Honolulú will arrive in San Francisco on Sunday.