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When any part of the body isn't doing the work that nature intended it to do, it puts the wholo system out of tune - out of harinony. Sickness in one part of the body is likely to run into aU parts of the body. When children stand a row of bricks on end they knock the wholo row down by upsetting one brick. That is exactly what happens to the health when tho bowels fail to perform their proper funotions. Constipation makes trouble all along tho line - puts the liver out of order, is bad for the kidneys- bad for the stomach, It Uolds in the body poisonous matter, and because it cannot go any place elso it iets into the blood. The blood carries it all over the system. That makes sluggishness, lassitude, bad breath and foul taste in the mouth, filis tho stomach with gas and causes windy belchiDg stops digestión in the stomach, heartburn and headacho You can avoid all such trouble, for Dr. Pierce's Pleaaant Pellets cure constipation and its attendevils, Send 21 cents in one-cent stamps to Dr. K. V. Pierce, Buffalo, N. Y., for hls "Medical Adviser." It is a book of 1008 pages, profusely ïllustrateü.