Ruth Zweifler was born 1929 in Palisades, New Jersey. She graduated from Bryn Mawr College, and converted from Judaism to Quakerism. Since the 1960s, she has been active in Civil Rights, anti-war, and anti-Zionist protests, including a sit-in at Ann Arbor City Hall protesting residential segregation. In 1975, Zweifler co-founded the Student Advocacy Center of Michigan, and she was Executive Director for nearly 30 years.
Ruth Zweifler was interviewed by students from Skyline High School in Ann Arbor in 2018 as part of the Legacies Project.